3D Tumoroid Scientist

Title of the Job: 3D Tumoroid Scientist

Location: Boston, MA

Job Description: Job DescriptionThe Cell Pharmacology group in the Department of Quantitative Biosciences is seeking a highly motivated Scientist with a background in immunology, oncology or cardiometabolic cellular assays to join our research laboratories in Boston. The primary tasks of the successful candidate will be to develop and characterize high throughput in vitro and ex vivo cell-based assays to support autoimmune, cancer, or cardiometabolic projects. These high throughput cell assays will use cell lines, primary human cells and human organoids.Responsibilities:Establish and characterize ex vivo translational models, including tumoroids and co-culture systems. Develop and optimize assays at scale to support potential compound screening, biomarker identification and mechanism of action studies.Characterize and optimize in vitro assays at scale to support potential compound screening, biomarker identification and mechanism of action studies.Evaluate the pharmacology of novel molecules, peptides, antibodies and other modalities for therapeutic potential in immunology, oncology or cardiometabolic indications.Work with both internal and external stakeholders and manage cell reagent sourcing activities.Maintain timely, accurate laboratory records of activities & comply with good documentation practices.Effectively partner with integrated teams in a matrix organizational setting to contribute to the conduct of studies and to the success of discovery programs.Required Education & Experience:B.S./B.A. degree with a minimum 3 years of full-time relevant work experience; or a M.S. degree with a minimum 1 year of full-time relevant work experience.Proficient in maintenance and troubleshoot of in vitro and ex vivo or translational or tumoroid models.Experiences with basic molecular biology techniques including PCR, qPCR, dPCR, Western blot, ELISA.Candidate should be a strong team player with excellent oral and written communication skills.Preferred Experience:Prior experience with primary human cells and ex vivo translational modelsExperience in the selection, optimization and characterization of effective immunology, oncology, or cardiometabolic assaysNOTICE FOR INTERNAL APPLICANTSIn accordance with all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.#EligibleforERPCurrent Employees applyCurrent Contingent Workers applyUS and Puerto Rico Residents Only:Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please if you need an accommodation during the application or hiring process.We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. 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Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance OrdinanceLos Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring OrdinanceSearch Firm Representatives Please Read Carefully
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Company Name: MSD

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